Slow access to MRS in our facility

Hello migrated to MRS in Jan 2022, however our site have been having issues with accessing MRS, It has become depressingly slow. We are currently running a windows server 2019 running on HP Gen 9 Server with 64g of Ram. I have run through my network for leakages, but network seems fine. Once upto 10 computers are on it become very very slow. any suggestions?

How many database instances are you running ?